Another antibiotic resistant bug is on the rise. The germ Clostridium difficile is an intestinal bug that is found in the colon. The germ Clostridium difficile germ is spread through spores found in feces. Persons infected with the germ may suffer with diarrhea. The germ can lead to a condition called colitis. The germ spores are resistant to most household cleaners and the antibacterial soaps, making it difficult to kill them.